Review -- fly models of ALS

Casci I, Pandey UB. A fruitful endeavor: Modeling ALS in the fruit fly. Brain Res. 2014 Oct 4. pii: S0006-8993(14)01337-7. PMID: 25289585.

From the abstract: "... Several Drosophila models have now been developed for studying the roles of ALS-associated genes in disease pathogenesis that allowed us to understand the molecular pathways that lead to motor neuron degeneration in ALS patients. Our primary goal in this review is to highlight the lessons we have learned using Drosophila models pertaining to ALS research."

Specific mutations in VPS35 associated with Parkinson's disease tested in flies

Wang HS, Toh J, Ho P, Tio M, Zhao Y, Tan EK. In vivo evidence of pathogenicity of VPS35 mutations in the Drosophila. Mol Brain. 2014 Oct 8;7(1):73. PMID: 25288323.

miRNA study using fly model of Alzheimer's diesase

Kong Y, Wu J, Yuan L. MicroRNA Expression Analysis of Adult-onset Drosophila Alzheimer's Disease Model. Curr Alzheimer Res. 2014 Oct 1. PMID: 25274109.

FlyRNAi: Drosophila cell-based genome-wide screen related t...

FlyRNAi: Drosophila cell-based genome-wide screen related t...: Ivatt RM, Sanchez-Martinez A, Godena VK, Brown S, Ziviani E, Whitworth AJ. Genome-wide RNAi screen identifies the Parkinson disease GWAS ri...