Copper, flies and Alzheimer's disease. Recent report.

Lang M, Fan Q, Wang L, Zheng Y, Xiao G, Wang X, Wang W, Zhong Y, Zhou B. Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms. Neurobiol Aging. 2013 Nov;34(11):2604-12.PMID: 23827522; PMCID: PMC3770863.

Flies & neuroblastoma. Recent report.

Chand D, Yamazaki Y, Ruuth K, Schönherr C, Martinsson T, Kogner P, Attiyeh EF, Maris J, Morozova O, Marra MA, Ohira M, Nakagawara A, Sandström PE, Palmer RH, Hallberg B. Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma. Dis Model Mech. 2013 Mar;6(2):373-82. PMID: 23104988; PMCID: PMC3597019.

Flies & Gaucher disease. Recent report.

Maor G, Rencus-Lazar S, Filocamo M, Steller H, Segal D, Horowitz M. Unfolded protein response in Gaucher disease: from human to Drosophila. Orphanet J Rare Dis. 2013 Sep 11;8(1):140. PMID: 24020503.

Flies & Huntington's Disease. Recent review.

Krench M, Littleton JT. Modeling Huntington disease in Drosophila: Insights into axonal transport defects and modifiers of toxicity. Fly (Austin). 2013 Sep 10;7(4). PMID: 24022020.

Fly study links intellectual disability gene and parkin-dependent mitophagy. Recent report.

Haddad DM, Vilain S, Vos M, Esposito G, Matta S, Kalscheuer VM, Craessaerts K, Leyssen M, Nascimento RM, Vianna-Morgante AM, De Strooper B, Van Esch H, Morais VA, Verstreken P. Mutations in the intellectual disability gene Ube2a cause neuronal dysfunction and impair parkin-dependent mitophagy. Mol Cell. 2013 PMID: 23685073.

From the abstract:  "we identify RAD6A as a regulator of Parkin-dependent mitophagy and establish a critical role for RAD6A in maintaining neuronal function."

Retinal degeneration-related fly study. Recent report.

Lee J, Song M, Hong S. Negative regulation of the novel norpA(P24) suppressor, diehard4, in the endo-lysosomal trafficking underlies photoreceptor cell degeneration. PLoS Genet. 2013 Jun;9(6):e1003559. doi: 10.1371/journal.pgen.1003559. PMID: 23754968; PMCID: PMC3674991.

Fly kidney stone model & juices. Recent report.

Ho CY, Chen YH, Wu PY, Chang CH, Chen HY, Man KM, Shen JL, Tsai FJ, Lin WY, Lee YJ, Chen WC. Effects of commercial citrate-containing juices on urolithiasis in a Drosophila model. Kaohsiung J Med Sci. 2013 Sep;29(9):488-93. PMID: 24018152.