Casci I, Pandey UB. A fruitful endeavor: Modeling ALS in the fruit fly. Brain Res. 2014 Oct 4. pii: S0006-8993(14)01337-7. PMID: 25289585.
From the abstract: "... Several Drosophila models have now been developed for studying the roles of ALS-associated genes in disease pathogenesis that allowed us to understand the molecular pathways that lead to motor neuron degeneration in ALS patients. Our primary goal in this review is to highlight the lessons we have learned using Drosophila models pertaining to ALS research."
Wednesday, October 8, 2014
Wang HS, Toh J, Ho P, Tio M, Zhao Y, Tan EK. In vivo evidence of pathogenicity of VPS35 mutations in the Drosophila. Mol Brain. 2014 Oct 8;7(1):73. PMID: 25288323.
Tuesday, October 7, 2014
Wednesday, October 1, 2014
FlyRNAi: Drosophila cell-based genome-wide screen related t...: Ivatt RM, Sanchez-Martinez A, Godena VK, Brown S, Ziviani E, Whitworth AJ. Genome-wide RNAi screen identifies the Parkinson disease GWAS ri...