Wednesday, October 8, 2014

Review -- fly models of ALS

Casci I, Pandey UB. A fruitful endeavor: Modeling ALS in the fruit fly. Brain Res. 2014 Oct 4. pii: S0006-8993(14)01337-7. PMID: 25289585.

From the abstract: "... Several Drosophila models have now been developed for studying the roles of ALS-associated genes in disease pathogenesis that allowed us to understand the molecular pathways that lead to motor neuron degeneration in ALS patients. Our primary goal in this review is to highlight the lessons we have learned using Drosophila models pertaining to ALS research."

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