Cardiomyopathies & the fly. Recent review.

This review provides background on key aspects of using Drosophila as a model system and discusses how the fly can be used to model cardiomyopathies. See especially Fig. 2.

From the review: "Drosophila genetics provides a powerful system to identify genes and pathways that potentially contribute to cardiomyopathies and serves as a platform to validate candidate human polymorphisms associated with cardiomyopathies."

Wolf MJ. Modeling dilated cardiomyopathies in Drosophila. Trends Cardiovasc Med. 2012 Apr;22(3):55-61. doi: 10.1016/j.tcm.2012.06.012. PubMed PMID: 22863366.