Wednesday, November 13, 2013

Fungal compound as possible environmental risk factor for Parkinson's Disease.

Inamdar AA, Hossain MM, Bernstein AI, Miller GW, Richardson JR, Bennett JW. Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration. Proc Natl Acad Sci U S A. 2013 Nov 11. PMID: 24218591.

From the abstract:  "... To date ... suspected environmental risk factors [for Parkinson's Disease] have been man-made chemicals. In this report, we demonstrate ... that the common volatile fungal semiochemical 1-octen-3-ol reduces dopamine levels and causes dopamine neuron degeneration in Drosophila melanogaster. ..."

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