Modeling neurodegenerative disease

Lepesant JA. The promises of neurodegenerative disease modeling. C R Biol. 2015 Aug-Sep;338(8-9):584-92. PMID: 26210484.

From the abstract: "The rise in the prevalence of neurodegenerative diseases parallels the rapid increase in human lifespan. Despite intensive research, the molecular and cellular mechanisms underlying the onset and progression of these devastating diseases with age are still poorly understood. ... This review will focus on the advantages offered by the genetic tools available in Drosophila for combining powerful strategies in order to tackle the causative factors of these complex pathologies and help to elaborate efficient drugs to treat them."