Friday, January 11, 2013

Studying obesity in model systems. Recent review.

From the abstract: "... we searched biological databases and discovered 33 additional genes associated with human obesity ... We find that the majority have orthologues in distant species, such as D. melanogaster ..." DIOPT finds additional putative fly orthologs not listed in their Table 1.

Williams MJ, Almén MS, Fredriksson R, Schiöth HB. What model organisms and interactomics can reveal about the genetics of human obesity. Cell Mol Life Sci. 2012 Nov;69(22):3819-34. doi: 10.1007/s00018-012-1022-5. Review. PubMed PMID: 22618246.

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