Pre-clinical drug trial for disease with currently "no disease-modifying treatments" includes Drosophila studies

This study focuses on Spinocerebellar ataxia type 3 (SCA3), which the authors indicate is also known as Machado-Joseph Disease (MJD).

Yi J, Zhang L, Tang B, Han W, Zhou Y, Chen Z, Jia D, Jiang H. Sodium valproate alleviates neurodegeneration in SCA3/MJD via suppressing apoptosis and rescuing the hypoacetylation levels of histone H3 and H4. PLoS One. 2013;8(1):e54792. PMID: 23382971; PMCID: PMC3557284.