Sunday, March 30, 2014

Patient alleles functionally tested in flies--cancer-related study

Gavilan HS, Kulikauskas RM, Gutmann DH, Fehon RG. In Vivo Functional Analysis of the Human NF2 Tumor Suppressor Gene in Drosophila. PLoS One. 2014 Mar 4;9(3):e90853. PMID: 24595234; PMCID: PMC3942481.

From the abstract:  "... Interestingly, we found that a patient-derived missense allele, NF2L64P, appears to be temperature sensitive. ..."

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