Saturday, May 10, 2014

Addressing metabolic issues in a fly model of Adenine Nuclear Translocase (ANT) insufficiency

Vartiainen S, Chen S, George J, Tuomela T, Luoto KR, O'Dell KM, Jacobs HT. Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease. Dis Model Mech. 2014 May 8. PMID: 24812436.

From the abstract: "... Our findings illustrate the potential of different therapeutic strategies for ANT-linked diseases, based on increasing mitochondrial bioenergy production, or on alleviating metabolic stress."

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