Nishihara S. Functional analysis of glycosylation using Drosophila melanogaster. Glycoconj J. 2019 Nov 26. doi: 10.1007/s10719-019-09892-0. PMID: 31773367.
From the abstract: "The glycosylation of proteins and lipids has various essential roles in a diverse range of biological processes ... detailed studies with Drosophila mutants of glycosyltransferases, nucleotide sugar transporters, and glycosidases revealed novel functions of N-linked glycans, glycosaminoglycans, glycolipids, and O-linked glycans including mucin type O-glycan, O-Fuc, O-Man, and O-GlcNAc. As many of these functions are common between Drosophila and humans, these mutants represent good models for human disease. In this review, recent studies of glycan functions using Drosophila are summarized."
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