Fatima A, Jyoti S, Siddique YH. Models of Parkinson's disease with special emphasis on Drosophila melanogaster. CNS Neurol Disord Drug Targets. 2018 Aug 20. PMID: 30129420.
Abstract: "Parkinson's disease is the second most common neurodegenerative disorder affecting more than 1% of the population average 60. The majority of PD cases are sporadic and are probably caused by a combination of risk factors but 5-10% of the PD cases are familial. Due to the high degree of gene conservation between humans, mice and insects using animal model system is a valuable approach to further elucidate the roles of the genes in PD. The present review highlights the models use to study PD symptoms with special emphasis on Drosophila."
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