Start learning about mycopolysaccharidoses on Wikipedia.
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Disease name, Human Gene ID, Human Gene Symbol, Inheritance pattern of the human genetic disease, FlyBase ID, Fly Gene Symbol, OMIM ID
- Mucopolysaccharidisis ["-osis"?] type IIIA (Sanfilippo A), 6448, SGSH, Autosomal recessive, FBgn0038660, CG14291, 605270
- Mucopolysaccharidosis Ih or Ih/s or Is, 3425, IDUA, Not reported, FBgn0032343, CG6201, 252800
- Mucopolysaccharidosis II, 3423, IDS, X-linked recessive, FBgn0035445, CG12014, 300823
- Mucopolysaccharidosis type IIIB (Sanfilippo B), 4669, NAGLU, Autosomal recessive, FBgn0014417, CG13397, 609701
- Mucopolysaccharidosis type IIIC (Sanfilippo C), 138050, HGSNAT, Autosomal recessive, FBgn0029737, CG6903, 610453
- Mucopolysaccharidosis type IIID, 2799, GNS, Autosomal recessive, FBgn0033836, CG18278, 607664
- Mucopolysaccharidosis VII, 2990, GUSB, Autosomal recessive, FBgn0034417, CG15117, 611499
With the exception of CG6201, there is evidence for expression of each of these in cultured S2R+ Drosophila cells.
OMIM refers to the Online Mendelian Inheritance in Man website at NCBI.
Wikipedia lists additional synonyms for sub-types of mucopolysaccharidosis, including Hurler syndrome, Hunter syndrome, Murquio syndrome, Maroteaux-Lamy syndrome, Sly syndrome and Natowicz syndrome.
Based on no other evidence than the fact that these fly genes have only systematic "CG#" names, not 'real' fly gene names, I'm guessing this is an under-studied group of genes in the fly.
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