Start learning about mycopolysaccharidoses on Wikipedia.
Get inspired by the U.S. MPS Society.
Disease name, Human Gene ID, Human Gene Symbol, Inheritance pattern of the human genetic disease, FlyBase ID, Fly Gene Symbol, OMIM ID
- Mucopolysaccharidisis ["-osis"?] type IIIA (Sanfilippo A), 6448, SGSH, Autosomal recessive, FBgn0038660, CG14291, 605270
- Mucopolysaccharidosis Ih or Ih/s or Is, 3425, IDUA, Not reported, FBgn0032343, CG6201, 252800
- Mucopolysaccharidosis II, 3423, IDS, X-linked recessive, FBgn0035445, CG12014, 300823
- Mucopolysaccharidosis type IIIB (Sanfilippo B), 4669, NAGLU, Autosomal recessive, FBgn0014417, CG13397, 609701
- Mucopolysaccharidosis type IIIC (Sanfilippo C), 138050, HGSNAT, Autosomal recessive, FBgn0029737, CG6903, 610453
- Mucopolysaccharidosis type IIID, 2799, GNS, Autosomal recessive, FBgn0033836, CG18278, 607664
- Mucopolysaccharidosis VII, 2990, GUSB, Autosomal recessive, FBgn0034417, CG15117, 611499
With the exception of CG6201, there is evidence for expression of each of these in cultured S2R+ Drosophila cells.
OMIM refers to the Online Mendelian Inheritance in Man website at NCBI.
Wikipedia lists additional synonyms for sub-types of mucopolysaccharidosis, including Hurler syndrome, Hunter syndrome, Murquio syndrome, Maroteaux-Lamy syndrome, Sly syndrome and Natowicz syndrome.
Based on no other evidence than the fact that these fly genes have only systematic "CG#" names, not 'real' fly gene names, I'm guessing this is an under-studied group of genes in the fly.