Tuesday, April 8, 2014

Receptor tyrosine kinase fly study with "potential implications" for cancer therapeutics

Macagno JP, Diaz Vera J, Yu Y, Macpherson I, Sandilands E, Palmer R, Norman JC, Frame M, Vidal M. FAK Acts as a Suppressor of RTK-MAP Kinase Signalling in Drosophila melanogaster Epithelia and Human Cancer Cells. PLoS Genet. 2014 Mar 27;10(3):e1004262. PMID: 24676055.

From the abstract: "... the FAK-mediated negative regulation of RTK/MAPK signalling described here may have potential implications in the designing of therapy strategies for RTK-driven tumours."

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