van der Voet M, Nijhof B, Oortveld MA, Schenck A. Drosophila models of early onset cognitive disorders and their clinical applications. Neurosci Biobehav Rev. 2014 Mar 21. pii: S0149-7634(14)00057-8. PMID: 24661984.
From the abstract: "... The available resources and efficiency of Drosophila place it in a position to tackle the main challenges in the field: mapping functional modules of ID [intellectual disability] genes to provide conceptually novel insights into the genetic control of cognition, tailored functional studies to improve 'next-generation' diagnostics, and identification of reversible ID phenotypes and medication. ... In conclusion, Drosophila provides many opportunities to advance future medical genomics of early onset cognitive disorders"