Monday, June 2, 2014

Methods review--use of Drosophila for heart-disease related studies

Ocorr K, Vogler G, Bodmer R. Methods to assess Drosophila heart development, function and aging. Methods. 2014 Apr 12. pii: S1046-2023(14)00133-9. PMID: 24727147.

From the abstract: "In recent years the Drosophila heart has become an established model for many different aspects of human cardiac disease. This model has allowed identification of disease-causing mechanisms underlying congenital heart disease and cardiomyopathies and has permitted the study of underlying genetic, metabolic and age-related contributions to heart function. In this review we discuss methods currently employed in the analysis of the Drosophila heart structure and function ..."

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