Friday, January 30, 2015

Sneak peak--'facelift' to DRSC website including our disease gene ortholog tool

We are undertaking a modest 'face lift' and update to our DRSC website.

Of interest to blog readers--one of the tools we're updating in look is our DIOPT-DIST resource.

DIOPT-DIST associates a fly gene (or other model species gene) with putative human orthologs, and also associates human orthologs with disease information (from OMIM or public GWAS data).

Here's a sneak peak of our new look. As of this post, the links will take you to our original pages, but be on the lookout for the updated look soon! Feedback welcome, now as always.

Here's the original publication describing DIOPT and DIOPT-DIST -- since updated to include an additional ortholog search algorithm and two more model species.

Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, Mohr SE. An integrative approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinformatics. 2011 Aug 31;12:357. PMID: 21880147

It's a BioMed Central 'Highly Accessed' publication and is freely available at PMC.

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