The interesting argument regarding p53, transposons, and cancer that is presented in this review draws in part from studies done in flies.
Wylie A, Jones AE, Abrams JM. p53 in the game of transposons. Bioessays. 2016 Nov;38(11):1111-1116. PMID: 27644006.
From the abstract: "Throughout the animal kingdom, p53 genes function to restrain mobile elements and recent observations indicate that transposons become derepressed in human cancers. ..."