This open access report includes follow-up of mammalian RNAi screen hits in a fly model of Huntington's disease.
Miller JP, Yates BE, Al-Ramahi I, Berman AE, Sanhueza M, Kim E, de Haro M, Degiacomo F, Torcassi C, Holcomb J, Gafni J, Mooney SD, Botas J, Ellerby LM, Hughes RE. A Genome-Scale RNA-Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease. PLoS Genet. 2012 Nov;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. PubMed PMID: 23209424.
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