Tuesday, December 18, 2012

Lowering A-beta. Recent report.

These authors report a study in flies that led to identification of a conserved protein that is a potential therapeutic target for neurodegenerative disease.

Page RM, Münch A, Horn T, Kuhn PH, Colombo A, Reiner O, Boutros M, Steiner H,
Lichtenthaler SF, Haass C. Loss of PAFAH1B2 Reduces Amyloid-β Generation by Promoting the Degradation of Amyloid Precursor Protein C-Terminal Fragments. J Neurosci. 2012 Dec 12;32(50):18204-18214. PubMed PMID: 23238734.

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