These authors use Drosophila as a model to look at tumor progression. They state that the results "provide a mechanistic basis for interclonal tumour progression driven by mitochondrial dysfunction and oncogenic Ras."
Ohsawa S, Sato Y, Enomoto M, Nakamura M, Betsumiya A, Igaki T. Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila. Nature. 2012 Oct 25;490(7421):547-51. doi: 10.1038/nature11452. PubMed PMID: 23023132.
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