Friday, April 12, 2013

Huntington's Disease & the fly. Wingless signaling & therapeutics.

Dupont P, Besson MT, Devaux J, Liévens JC. Reducing canonical Wingless/Wnt signaling pathway confers protection against mutant Huntingtin toxicity in Drosophila. Neurobiol Dis. 2012 Aug;47(2):237-47. doi: 10.1016/j.nbd.2012.04.007. PubMed PMID: 22531500.

From the abstract: "Our findings highlight that restoring canonical Wg/Wnt signaling may be of therapeutic value."

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