Friday, April 12, 2013

Two reports involving human tau-based fly disease models. Recent report.

Xiong Y, Zhao K, Wu J, Xu Z, Jin S, Zhang YQ. HDAC6 mutations rescue human tau-induced  microtubule defects in Drosophila. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4604-9. doi: 10.1073/pnas.1207586110. PubMed PMID: 23487739; PubMed Central PMCID: PMC3606981.

Wu TH, Lu YN, Chuang CL, Wu CL, Chiang AS, Krantz DE, Chang HY. Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau. Acta Neuropathol. 2013 Mar 15. PubMed PMID: 23494099.

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