Friday, April 12, 2013

Huntington's Disease. Validation of a fly model. Recent report.

Zala D, Hinckelmann MV, Saudou F. Huntingtin's Function in Axonal Transport Is Conserved in Drosophila melanogaster. PLoS One. 2013;8(3):e60162. PubMed PMID: 23555909; PubMed Central PMCID: PMC3610688.

From the abstract: "These results suggest that the function of HTT in axonal transport is conserved between flies and mammals. Our study therefore validates Drosophila melanogaster as a model to study HTT function, and its dysfunction associated with HD."

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