Monday, November 17, 2014

'Spliceosensor' in flies for high-throughput screening related to myotonic dystrophy

García-Alcover I, Colonques-Bellmunt J, Garijo R, Tormo JR, Artero R, Alvarez-Abril MC, López Castel A, Pérez Alonso M. Development of a Drosophila melanogaster spliceosensor system for in vivo high-throughput screening in myotonic dystrophy type 1. Dis Model Mech. 2014 Sep 19. pii: dmm.016592. PMID: 25239918.

From the abstract: "... This powerful Drosophila-based screening tool might also be applied in other  disease models displaying abnormal alternative splicing, thus offering myriad uses in drug discovery."

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