Thursday, May 28, 2015

Review--flies, iron and neurodegenerative diseases

Zhu ZJ, Wu KC, Qian ZM, Yung WH, Ke Y. Drosophila models for studying iron-related neurodegenerative diseases. Sheng Li Xue Bao. 2014 Feb 25;66(1):47-54. PMID: 24553869.

From the abstract: "In recent years, iron has been regarded as a common pathological feature of many neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD) and Friedreich's ataxia (FRDA). ...  characteristics ... turn Drosophila into an excellent in vivo genetic system for screening iron-related modifiers in different neurodegenerative conditions ... "

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