Thursday, May 28, 2015

Review looks at fly and mouse models of Fragile X syndrome

Santos AR, Kanellopoulos AK, Bagni C. Learning and behavioral deficits associated with the absence of the fragile X mental retardation protein: what a fly and mouse model can teach us. Learn Mem. 2014 Sep 16;21(10):543-55. PMID: 25227249; PMCID: PMC4175497.

From the abstract: "... Here, we review to which extent these biological models are affected by the absence of FMRP, pointing out the similarities with the observed human dysfunction. Additionally, we discuss several potential treatments under study in animal models that are able to partially revert some of the FXS abnormalities. "

No comments:

Post a Comment