Tuesday, May 26, 2015

Review includes contribution of model systems to understanding lipodystrophies and dyslipidemias

Prieur X, Le May C, Magré J, Cariou B. Congenital lipodystrophies and dyslipidemias. Curr  Atheroscler Rep. 2014 Sep;16(9):437. PMID: 25047893.

From the abstract:  "... The precise mechanisms by which the lack of adipose tissue causes dyslipidemia remain largely unknown. In recent years, new insights have arisen from data obtained in vitro in adipocytes, yeast, drosophila, and very recently in several genetically modified mouse models of generalized lipodystrophy. ..."

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