Saturday, November 17, 2012

BEACH and flies. Recent report.

This study includes a comparison of phenotypes rescued by mouse and fly Neurobeachin transcripts (fly rugose). The results have implications in understanding BEACH, or beige and human Chediak-Higashi syndrome.

Volders K, Scholz S, Slabbaert JR, Nagel AC, Verstreken P, Creemers JW, Callaerts P, Schwärzel M. Drosophila rugose Is a Functional Homolog of Mammalian Neurobeachin and Affects Synaptic Architecture, Brain Morphology, and Associative Learning. J Neurosci. 2012 Oct 24;32(43):15193-204. doi:10.1523/JNEUROSCI.6424-11.2012. PubMed PMID: 23100440.

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