This report describes use of Drosophila and mammalian systems to uncover links between PolyQ disease and nucleolar stress.
Tsoi H, Lau TC, Tsang SY, Lau KF, Chan HY. CAG expansion induces nucleolar stress in polyglutamine diseases. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13428-33. doi: 10.1073/pnas.1204089109. PubMed PMID: 22847428; PubMed Central PMCID: PMC3421186.
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