CG17119, the fly, cystinosis, and the future.

CG17119 is a high-confidence putative ortholog of the human gene CTNS, which has been implicated in cystinosis. Results from the DIOPT-DIST are shown below. Phenotypic data in FlyBase, as of this posting, is summarized "No phenotypic data is available."

Fly stocks designed for RNAi knockdown of CG17119 are available from BDSC (TRiP lines) and VDRC. This is just one example of a fly ortholog of a human disease gene. Will it be you who puts the tools in hand to use to study this disease, or another, using the fly?

Click to enlarge or visit www.flyrnai.org/diopt-dist to replicate the search.