Zhu H, Han M. Exploring developmental and physiological functions of fatty acid and lipid variants through worm and fly genetics. Annu Rev Genet. 2014;48:119-48. PMID: 25195508.
From the abstract: "Lipids are more than biomolecules for energy storage and membrane structure. With ample structural variation, lipids critically participate in nearly all aspects of cellular function. Lipid homeostasis and metabolism are closely related to major human diseases and health problems. However, lipid functional studies have been significantly underdeveloped ... Here, we review a subset of these studies using Caenorhabditis elegans and Drosophila melanogaster."