Thursday, June 6, 2013

Injury, the gut and cancer. Recent report.

Guo Z, Driver I, Ohlstein B. Injury-induced BMP signaling negatively regulates Drosophila midgut homeostasis. J Cell Biol. 2013 Jun 3. PMID: 23733344.

From the abstract: "Loss of BMP signaling pathway members ...  resulted in phenotypes similar to those described for juvenile polyposis syndrome ... Our data ... may provide insight into how BMP signaling mutations drive formation of human intestinal cancers."

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