In this paper, the authors describe disruption of Drosophila BHD (Folliculin), an ortholog of a tumor suppressor gene associated with the inherited skin disorder Birt-Hogg-Dubé Syndrome. They go on to characterize the mutant phenotype and look at the impact of nutritional interventions on phenotype severity.
Liu W, Chen Z, Ma Y, Wu X, Jin Y, Hou S. Genetic Characterization of the Drosophila Birt-Hogg-Dubé Syndrome Gene. PLoS One. 2013 Jun 17;8(6):e65869. PMID: 23799055.
From the abstract: "Our work provides a new animal model of the BHD syndrome and suggests that modulation of the local nutrient condition might be a potential treatment of the BHD lesions."