Thursday, August 9, 2012

Drosophila, chemical genetics and cancer. Recent Report.

Dar AC, Das TK, Shokat KM, Cagan RL. Chemical genetic discovery of targets and anti-targets for cancer polypharmacology. Nature. 2012 Jun 6;486(7401):80-4. doi: 10.1038/nature11127. PubMed PMID: 22678283.

From the abstract:
Combining kinase-focused chemistry, kinome-wide profiling and Drosophila genetics provides a powerful systems approach towards developing compounds with maximal therapeutic index.

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