Thursday, August 2, 2012

Spinocerebellar ataxia 1 stocks at the BDSC

Spinocerebellar ataxia type 1 (SCA1) is a progressive neurological disease caused by increases in the number of CAG repeats in the Ataxin 1 (ATXN1) gene. The Bloomington Drosophila Stock Center has recently acquired strains carrying human ATXN1 with differing numbers of CAG repeats for modeling SCA1 in flies (generated in Fernandez-Funez et al., 2000. Nature 408:101 pmid:11081516).

See these and other fly strains useful for studying SCA1 at the BDSC's SCA1 page.

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