Monday, August 27, 2012

Fly seizure models and drug resistance. Recent report.

Bao GS, Wang WA, Wang TZ, Huang JK, He H, Liu Z, Huang FD. Overexpression of human MRP1 in neurons causes resistance to antiepileptic drugs in Drosophila seizure mutants. J Neurogenet. 2011 Dec;25(4):201-6. Epub 2011 Oct 25. PubMed PMID: 22026728

Seizure model used: flies carrying a mutation in bang senseless, which has the official FlyBase name paralytic and the FlyBase ID FBgn0264255.

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