The review includes a nice figure of the fly cardiovascular system (Fig. 2) and this statement in the Conclusions section:
Although the adult fly heart is a single cell layer thick and does not possess noncardiac cells found in mammalian hearts, the Drosophila model provides a system to examine the direct effects of gene mutations on size, morphology, and function of cardiomyocytes ... Ongoing investigations of the fly as a model for human cardiomyopathies have the potential to uncover new, fundamental mechanisms that are responsible for human cardiovascular diseases.
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