Tuesday, August 7, 2012

Heat-shock proteins and heart disease. Recent Review.

Hoogstra-Berends F, Meijering RA, Zhang D, Heeres A, Loen L, Seerden JP, Kuipers I, Kampinga HH, Henning RH, Brundel BJ. Heat Shock Protein-Inducing Compounds as Therapeutics to Restore Proteostasis in Atrial Fibrillation. Trends Cardiovasc Med. 2012 Aug 2. PubMed PMID: 22863365.

Atrial Fibrillation is a type of tachyarrhythmia of the heart.

This paper describing a Drosophila model of tachycardia is cited in the Hoogstra-Berends et al. review:  Zhang D, Ke L, Mackovicova K, Van Der Want JJ, Sibon OC, Tanguay RM, Morrow G, Henning RH, Kampinga HH, Brundel BJ. Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation. J Mol Cell Cardiol. 2011 Sep;51(3):381-9. PubMed PMID: 21745477

Watch the fly heart beat here:

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