Inflammatory bowel disease and the fly. Recent review.

This review introduces the fly gut system, summarizes major pathways invoked in gut-microbe responses and talks about gut homeostasis. The results and approaches discussed might impact our understanding of human diseases of the digestive system, including inflammatory bowel disease.

Charroux B, Royet J. Gut-microbiota interactions in non-mammals: what can we learn from Drosophila? Semin Immunol. 2012 Feb;24(1):17-24. Epub 2012 Jan 28. Review. PubMed PMID: 22284578.