Tuesday, October 16, 2012

New fly model of genetic epilepsy with febrile seizures plus. Recent report.

In this study, researchers introduce a human disease-associated mutation into the fly ortholog of SCN1A, para.

Sun L, Gilligan J, Staber C, Schutte RJ, Nguyen V, O'Dowd DK, Reenan R. A knock-in model of human epilepsy in Drosophila reveals a novel cellular mechanism associated with heat-induced seizure. J Neurosci. 2012 Oct 10;32(41):14145-55. doi: 10.1523/JNEUROSCI.2932-12.2012. PubMed PMID: 23055484.

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