Thursday, August 14, 2014

Flies and sea anemones as models for the study of noise-induced hearing loss

Christie KW, Eberl DF. Noise-induced hearing loss: new animal models. Curr Opin Otolaryngol Head Neck Surg. 2014 Aug 8. PMID: 25111054.

From the abstract: "... Work on sea anemone hair bundles, which resemble auditory hair cells, has revealed secretions that exhibit astonishing healing properties ... for damaged hair bundles ... The second model, the Johnston's organ in Drosophila, is also genetically homologous to hair cells and shows noise-induced hearing loss similar to vertebrates. Drosophila offers genetic and molecular insight into noise sensitivity and pathways that can be manipulated to reduce stress and damage from noise. ... Expanding study of these systems may accelerate identification of strategies to reduce or prevent noise damage in the human ear."

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